吴伟-凯发娱乐官网

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基本情况

吴伟，1992年和1996年毕业于第二军医大学药学院，分别获理学学士和医学硕士学位；1999年毕业于华西医科大学药剂学专业，获理学博士学位。2000年进入复旦大学药学院任教，现为药剂学教研室教授、博导。2007年至2012年曾任科研副院长。兼任：sfda新药审评专家；国家药品价格审评专家；中国药学会药剂专业委员会委员；中华中医药学会制剂分会常委、中成药分会常委；中国颗粒学会生物颗粒专委会委员；上海药学会制药工程专委会委员、药剂专委会委员；《中国医药工业杂志》、arch pharm res, asian j pharm sci, jchin pharm sci, nanomed nanobiol等十余本期刊编委。主要从事药剂学的教学和科研工作，主要研究方向为微粒和纳米给药系统、口服给药系统、天然药物新型给药系统。主编《现代中药研究与开发》，参编十一五、十二五全国规划教材《药剂学》、《生物药剂学与药物动力学》等。主持国家及省部级研究课题10余项，授权专利5项，开发新药10余项，发表论文130余篇，其中sci论文60余篇。曾获中国药学会－石药集团青年药剂学奖、上海市优秀教学成果二等奖、上海药学科技三等奖、军队科技进步三等奖等。教育部新世纪优秀人才、上海市曙光学者、上海高校优秀青年教师。

 

研究领域

微粒和纳米给药系统、口服给药系统、天然药物新型给药系统

 

论文发表

  1. mengmeng niu, ya’nan tan, peipei guan, lars hovgaard, yi lu, jianping qi, ruyue lian, xiaoyang li, wei wu*. enhanced oral absorption of insulin-loaded liposomes containing bile salts: a mechanistic study. int j pharm 2014, 460: 119-130
  2. xingwang zhang, jianping qi, yi lu, xiaoyang li, wei he, wei wu*. biotinylated liposomes as potential carriers for oral delivery of insulin. nanomedicine: nanotech biol med 2014, 10: 167-176
  3. bei zhang, jian chen, yi lu, jianping qi, wei wu*. liposomes interiorlythickened with thermosensitive nanogelas novel drug delivery systems. int j pharm 2013, 455: 276-284
  4. wei he, yi lu, jianping qi, lingyun chen, lifang yin, wei wu*. formulating food protein-stabilized indomethacinnanosuspensionsinto pellets by fluid-bed coating technology: physical characterization, redispersibility and dissolution. int j nanomedicine 2013, 8: 3119-3128
  5. zhiqiang tian, jianping qi*, yueneng yi, jin han, hailong yuan, xi zhang, yunchang xie, fuqiang hu, yi lu, wei wu*. solidification of nanostructured lipid carrier (nlc) onto pellets by fluid-bed coating: preparation, in vitro characterization and bioavailability in dogs. powd tech 2013, 247: 120-7
  6. xi zhang, yueneng yi, jianping qi, yi lu, zhiqiang tian, yunchang xie, fuqiang hu, hailong yuan, wei wu*. controlled release of self-nanoemulsifying systems fromosmotic pump tablets: near zero-order release in vitro and pharmacokinetics in dogs. int j pharm2013, 452: 233-240
  7. wei he, yi lu, jianping qi, lingyun chen, fuqiang hu,wei wu*. nanoemulsion-templated shell-crosslinked nanocapsules as drug delivery systems. int j pharm 2013, 445: 69-78
  8. yunchang xie, yi lu, jianping qi, xiaoyang li, xi zhang, jin han, shixiao jin, hailong yuan*, wei wu*. synchronized and controlledrelease of multiple components in silymarin achieved by the osmotic release strategy. int j pharm2013, 441: 111-120
  9. wei he, yi lu, jianping qi, lingyun chen, fuqiang hu, wei wu*. food proteins as novel nanosuspension stabilizers for poorly water-soluble drugs. int j pharm2013, 441: 269-278
  10. shunwen hu, mengmeng niu,fuqiang hu, yi lu, jianping qi, zongning yin*, wei wu*. integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. int j pharm2013, 441: 693-700
  11. xiaoyang li, jianping qi*, yunchang xie, xi zhang, shunwen hu, ying xu, yi lu, wei wu*. nanoemulsions coated with alginate/chitosan as oral insulin delivery systems: preparation, characterization and hypoglycemic effect in rats. int j nanomedicine2013, 8: 23-32
  12. yi lu, tao guo, jian-ping qi, ji-wen zhang*, wei wu*. enhanced dissolution and stability of lansoprazole by cyclodextrin inclusion complexation: preparation, characterization and molecular modeling. aaps pharmscitech2012, 13(4): 1222-1229
  13. ying xu, xiaoyi liu, ruyue lian, siyi zheng, zongning yin, yi lu*, wei wu*. enhanced dissolution and oral bioavailability ofaripiprazole nanosuspensionsprepared by nanoprecipitation/homogenizationbased on acid-base neutralization. int j pharm 2012, 438: 287-295
  14. shixiao jin, shanshan fu, jin han, shiying jin, qingyuan lv, yi lu, jianping qi,wei wu*, hailong yuan*. improvement of oral bioavailability of glycyrrhizin bysodium deoxycholate/phospholipid-mixed nanomicelles. j drug target, 2012, 20 (7): 615–622
  15. mengmeng niu, yi lu, lars hovgaard, peipei guan, yanan tan, ruyue lian, jianping qi, wei wu*. hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. eur j pharm biopharm2012 81(2): 265-72
  16. yi lu, jianping qi, peipei guan, yuzhang hu, keping ruan, wei wu*. micronization of solid dispersion pellets: physical characterization and improved dissolution. adv sci lett 2012(6): 200-206(7)


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